A narrative systematic review (Razaghizad et al., 2021, studies = 11 RCTs and 17 non-RCTs, N = 33,711 of 37,117 active research participants aged 15-25 yrs) investigated the effectiveness of prevention interventions for drugs-and-driving outcomes. The results found evidence to support the interventions that may improve drugs and driving knowledge, attitudes, and behaviours, specifically: 

• high quality evidence that cannabis packaging with health warnings increases the knowledge about drugged driving effects
• moderate quality evidence that roadside drug testing can reduce drugs-and-driving among cannabis users
• moderate quality evidence that for youth or previous offenders, motivational interviewing can prevent drug-and-driving and driver education programs can increase knowledge

The impact of such interventions on measures of drugs-and-driving morbidity and mortality outcomes is uncertain.