Neurostimulation techniques to prevent surgery-induced opioid dependence — evidence summary

Summary of the evidence

Unknown effectiveness

A systematic review without meta-analysis (Gallucci et al 2018, 7 clinical trials, n= 292) found that five clinical trials observed a statistically significant reduction in postoperative opioid consumption (patient controlled analgesia) following cortical stimulation to treat postoperative pain (additionally, one trial found no statistically differences, and another found both an increase and decrease depending on the positioning of the anode).


Note: this evidence summary is only valid for the outcomes, target groups, settings and substances/patterns of use described below.

Name of response option:
Neurostimulation techniques
Desired outcome(s):
reduce substance use
Specific substance or pattern of use:

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